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Results Found: 2
  • Murine vagus nerve recordings after cytokine injection
    Internal Dataset

    Authors
    Theodoros Zanos
    Harold Silverman
    Todd Levy
    Tea Tsaava
    6 more author(s)...
    Description

    These datasets were generated during a study to develop methods to isolate and decode specific neural signals to discriminate between two different cytokines. Nerve impulses recorded from the vagus nerve of mice exposed to IL-1B and TNF were sorted into groups based on their shape and amplitude, and their respective firing rates were computed. These cytokine-mediated responses were subsequently decoded....

    Subject
    Electrophysiology
    mice
    Vagus Nerve
  • Cholinergic Anti-inflammatory Pathway (CAP) Activation in a Model of Acute Lung Infection
    Internal Dataset

    Authors
    John Graf
    Umair Ahmed
    Anthony Liew
    Annette Lee
    2 more author(s)...
    Description

    The cholinergic anti-inflammatory pathway (CAP), has been well-studied and shown to control peripheral cytokine levels and inflammation. This nerve pathway has been activated pharmacologically or by nerve stimulators and studied in animal models and clinical studies. However, these CAP investigations have typically been performed in models or study populations of severe systemic or pathological inflammation....

    Subject
    Genomics
    Inflammation
    Rats
    RNA-Seq
    Access Rights
    Free to All
    Local Expert
    Stavros Zanos

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